Identification of 14 Known Drugs as Inhibitors of the Main Protease of SARS-CoV-2
M. M. Ghahremanpour, J. Tirado-Rives, M. Deshmukh, J. A. Ippolito, C.-H. Zhang, I. Cabeza de Vaca, M.-E. Liosi, K. S. Anderson, W. L. Jorgensen
The paper identifies 14 known drugs that inhibit SARS-CoV-2 main protease, with five showing IC50 values below 40 μM.
bioRxiv · Aug 28, 2020Pharmacology & Toxicology