Author

M. Deshmukh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Cell Biology· 1 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

E. Hollville· 2 shared S. Kapoor· 2 shared A. B. Lopez· 1 shared A. Nakamura· 1 shared C. Flowers· 1 shared C. L. Kurtz· 1 shared C. Lopez-Otin· 1 shared C. Sihlbom· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersPhysiology

E. Hollville

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

miR-29 is an important driver of aging-related phenotypes

V. Swahari, A. Nakamura, E. Hollville, Y.-H. Hung, M. Kanke, C. L. Kurtz, X. M. Caravia, S. He, J. Krishnamurthy, S. Kapoor, V. Prasad, C. Flowers, M. Beck, J. Baran-Gale, N. Sharpless, , M. Deshmukh

This study identifies miR-29 as a key driver of aging-related phenotypes by showing its upregulation in aging models and its ability to induce aging traits when overexpressed.

bioRxiv · Nov 29, 2022Physiology

Constitutive high expression of NOXA sensitizes human embryonic stem cells for rapid cell death

R. Basundra, S. Kapoor, E. Hollville, N. Kiapour, A. B. Lopez, N. M. Melchiorre, M. Deshmukh

This study shows that high NOXA levels in hES cells antagonize MCL1, enabling rapid apoptosis in response to DNA damage.

bioRxiv · Jan 13, 2021Cell Biology

Differential fate of acellular vascular scaffolds in vivo involves macrophages and T-cell subsets

D. Banerjee, N. B. Nayakawde, D. Antony, M. Deshmukh, S. Ghosh, C. Sihlbom, E. Berger, U. Ul Haq, M. Olausson

This study compares natural and chemically decellularized vascular scaffolds in vivo, showing site-specific immune responses and identifying immunological triggers without immunosuppression.

bioRxiv · Nov 21, 2020Bioengineering

Identification of 14 Known Drugs as Inhibitors of the Main Protease of SARS-CoV-2

M. M. Ghahremanpour, J. Tirado-Rives, M. Deshmukh, J. A. Ippolito, C.-H. Zhang, I. Cabeza de Vaca, M.-E. Liosi, K. S. Anderson, W. L. Jorgensen

The paper identifies 14 known drugs that inhibit SARS-CoV-2 main protease, with five showing IC50 values below 40 μM.

bioRxiv · Aug 28, 2020Pharmacology & Toxicology

Structural Insights into Curli CsgA Cross-β Fibril Architecture Inspired Repurposing of Anti-amyloid Compounds as Anti-biofilm Agents

S. Perov, O. Lidor, N. Salinas, N. Golan, E. Tayeb-Fligelman, M. Deshmukh, D. Willbold, M. Landau

This paper reveals structural similarities between bacterial curli amyloids and human pathological amyloids, leading to the repurposing of anti-amyloid drugs as anti-biofilm agents.

bioRxiv · Jan 18, 2019 · PreprintBiochemistry