BiochemistrybioRxiv
Altered specificity of 15-LOX-1 in the biosynthesis of 7S,14S-diHDHA implicates 15-LOX-2 in biosynthesis of resolvin D5
S. C. Perry, C. Kalyanaraman, B. E. Tourdot…·T. R. Holman
This paper identifies that h15-LOX-2 preferentially produces RvD5 from 7S-HDHA with faster kinetics than h15-LOX-1, suggesting a greater role for h15-LOX-2 in biosynthesizing resolvin D5.
DOI 10.1194/jlr.ra120000777