Genetic analysis of isoform usage in the human anti-viral response reveals influenza-specific regulation of ERAP2 transcripts under balancing selection
Chun Ye, Jenny Chen, Alexandra–Chloé Villani, Rachel E. Gate, Meena Subramaniam, Tushar Bhangale, Mark N. Lee, Towfique Raj, Raktima Raychowdhury, Weibo Li, Noga Rogel, Sean Simmons, Selina H. Imboywa, Portia I. Chipendo, Cristin Aubin, , Nir Hacohen
The paper identifies genetic variants influencing isoform usage in the anti-viral response, revealing ERAP2's role in balancing selection and influenza-specific regulation.
Genome Research · Dec 1, 2018Peer-reviewedGenomics