Author

Noga Rogel

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:GWAS / association mapping· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Aviv RegeviD· 4 shared Adam L. HaberiD· 2 shared Alex K. ShalekiD· 2 shared Alexandra–Chloé VillaniiD· 2 shared Daniel B. GrahamiD· 2 shared Grace Burgin· 2 shared Jenny CheniD· 2 shared Moshe BitoniD· 2 shared

Activity by Year

2017-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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4 shared papersGenomics

Aviv RegevORCID

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Author profile →

4 papers

Recent·Most cited

Rewiring of the cellular and inter-cellular landscape of the human colon during ulcerative colitis

Christopher S. Smillie, Moshe Biton, José Ordovás-Montañés, Keri M. Sullivan, Grace Burgin, Daniel B. Graham, Rebecca H. Herbst, Noga Rogel, Michal Slyper, Julia Waldman, Malika Sud, Elizabeth Andrews, Adam L. Haber, Sanja Vicković, Danielle Ashley Dionne, , Aviv Regev

The paper was withdrawn due to the inclusion of confidential information about a third party.

bioRxiv · May 25, 2019 · PreprintGenomics

A quantitative model for characterizing the evolutionary history of mammalian gene expression

Jenny Chen, Ross Swofford, Jeremy Johnson, Beryl B. Cummings, Noga Rogel, Kerstin Lindblad‐Toh, Wilfried Haerty, Federica Di Palma, Aviv Regev

The paper uses an OU process to model gene expression evolution across mammals and identifies expression pathways under different selection pressures.

Genome Research · Jan 1, 2019Peer-reviewedGenomics

Genetic analysis of isoform usage in the human anti-viral response reveals influenza-specific regulation of ERAP2 transcripts under balancing selection

Chun Ye, Jenny Chen, Alexandra–Chloé Villani, Rachel E. Gate, Meena Subramaniam, Tushar Bhangale, Mark N. Lee, Towfique Raj, Raktima Raychowdhury, Weibo Li, Noga Rogel, Sean Simmons, Selina H. Imboywa, Portia I. Chipendo, Cristin Aubin, , Nir Hacohen

The paper identifies genetic variants influencing isoform usage in the anti-viral response, revealing ERAP2's role in balancing selection and influenza-specific regulation.

Genome Research · Dec 1, 2018Peer-reviewedGenomics

T helper cells modulate intestinal stem cell renewal and differentiation

Moshe Biton, Adam L. Haber, Semir Beyaz, Noga Rogel, Christopher Smillie, Karthik Shekhar, Alexandra Schnell, Zuojia Chen, Chuan Wu, Jose Ordovas-Montanes, David Alvarez, Rebecca H. Herbst, Itay Tirosh, Grace Burgin, Danielle Dionne, , Ramnik J. Xavier

This study shows that T helper cells interact with intestinal stem cells via MHCII to regulate their renewal and differentiation, with distinct effects based on Th subtype and cytokine signaling.

bioRxiv · Nov 14, 2017 · PreprintImmunology