Nuclear size-regulated emergence of topological packing order on growing human lung alveolospheres
Wenhui Tang, Jessie Huang, Adrian F. Pegoraro, James H. Zhang, Yiwen Tang, Dapeng Bi, Darrell N. Kotton, Ming Guo
This study shows that cell packing order in human lung alveolospheres increases with nucleus-to-cell size ratio, resembling a gas-to-liquid transition, and may regulate organ development and maturation.
bioRxiv · Apr 17, 2024 · PreprintBiophysics