PDGFRα-directed fibroblast-homing peptides for targeted delivery of nucleic acid therapeutics
Shuzhi Cheng, Will Weston, Pierpaolo Ala, Jennifer C. Chandler, William J. Mason, Heloise Vinette, Wendy Heywood, Rachael Dickman, Francesco Muntoni A, Sara Aguti, Haiyan Zhou
The paper identifies fibroblast-homing peptides targeting PDGFR for targeted delivery of nucleic acid therapeutics, showing enhanced efficacy in a collagen VI-related muscular dystrophy model.
bioRxiv · Oct 20, 2026 · PreprintMolecular Biology