Author

William L Hamilton

University of CambridgePrimary ORCID profile (0000-0002-3330-353X · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

William L HamiltoniD1 paper · University of Cambridge

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:whole-genome sequencing· 2 Approach:experimental assay· 1 Research Focus:genome assembly· 1 Organism:plant (other)· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Organism:virus· 1

Frequent Co-Authors

Alex Alderton· 1 shared Alex MakuniniD· 1 shared Aminu S Jahun· 1 shared Andrew R J Lawson· 1 shared Anna Yakovleva· 1 shared Antoine ClaessensiD· 1 shared Camille CoheniD· 1 shared Charlotte J. HouldcroftiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenomics

Alex Alderton

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2 papers

Recent·Most cited

De novo assembly of complete Plasmodium falciparum isolate genomes using PacBio HiFi sequencing technology

Prince Nyarko, Mathieu Quenu, Marc-Antoine Guery, Camille Cohen, Godfrey Kinyori Wagutu, William L Hamilton, Sophia T. Girgis, Alex Makunin, Shane McCarthy, Mara Lawniczak, Antoine Claessens

This study uses PacBio HiFi sequencing to assemble complete Plasmodium falciparum genomes from natural infections, revealing full repertoires of immune-related genes.

G3 Genes Genomes Genetics · Oct 27, 2026Peer-reviewedGenomics

Patterns of within-host genetic diversity in SARS-CoV-2

Gerry Tonkin-Hill, Iñigo Martincorena, Roberto Amato, Andrew R J Lawson, Moritz Gerstung, Ian Johnston, David K Jackson, Naomi R Park, Stefanie V Lensing, Michael A Quail, Sónia Gonçalves, Cristina Ariani, Michael Spencer Chapman, William L Hamilton, Luke W Meredith, , Dominic Kwiatkowski

This study analyzes within-host genetic diversity in 1,181 SARS-CoV-2 samples, finding high mutation rates, strand asymmetries, and purifying selection, with implications for transmission chain reconstruction.

eLife · Aug 13, 2021Peer-reviewedGenomics