Author
Wellcome Sanger Institute
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Gerry Tonkin-Hill, Iñigo Martincorena, Roberto Amato…·Dominic Kwiatkowski
This study analyzes within-host genetic diversity in 1,181 SARS-CoV-2 samples, finding high mutation rates, strand asymmetries, and purifying selection, with implications for transmission chain reconstruction.
Bogdan Andrei Mirauta, Daniel D. Seaton, Dalila Bensaddek…·Philip L. Beales
The paper characterizes proteome variation across 202 human iPSC lines, identifies 700 pQTLs, and links pQTLs to disease-associated GWAS variants.
Anna S. E. Cuomo, Daniel D. Seaton, Davis James McCarthy…·Oliver Stegle
The paper uses single-cell RNA-seq of differentiating iPS cells from 125 donors to identify expression quantitative trait loci influencing gene expression during endoderm differentiation.
Helena Kilpinen, Angela Goncalves, Andreas Leha…·Daniel J Gaffney
This study analyzes 522 human iPSCs to identify genetic sources of phenotypic variation, finding 5-25% of variation in traits like differentiation capacity is due to individual differences.