Dynamic Fluoroleucine PET Detects Impaired Cardiac Leucine Uptake Before Hypertensive Left Ventricular Hypertrophy Develops
William Terrell, Jie Li, Damodara Naidu Kommi, Megan Burt, Maurits A. Jansen, Shivashankar Khanapur, Susanna R. Keller, Bijoy Kundu
This paper uses [18F]FLE-PET/CT to detect reduced cardiac leucine uptake in hypertensive rats before LVH develops, suggesting it as an early marker for cardiometabolic dysfunction.
bioRxiv · May 14, 2026 · PreprintBioengineering