Orai1 is required for Ca2+-dependent plasma membrane repair and mechanoadaptation
Haitao Luan, Azize Çerçi, Timothy Alan Bielecki, Bhopal C. Mohapatra, Santosh Shrestha, William Wu, Matthew D. Storck, Lynette M. Smith, Kenneth A. Stauderman, Donald W. Coulter, Anupam Kotwal, Jixin Dong, Jung Yul Lim, Vimla Band, Subramanian P. Ramanathan, Hamid Band
This study identifies Orai1 and EHD2 as essential for Ca2+-dependent plasma membrane repair and mechanoadaptation in response to mechanical injury and bacterial toxins.
bioRxiv · May 15, 2026 · PreprintCell Biology