Author

Wouter M. Thomas

Royal Netherlands Academy of Arts and Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:scRNA-seq· 2 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Katharina F. SonneniD· 3 shared Marek J. van OostromiD· 3 shared Wilke H. M. MeijeriD· 3 shared Sonja D. C. WeteringsiD· 2 shared Balaji Srinivasan· 1 shared Benjamin D. SimonsiD· 1 shared Charis FountasiD· 1 shared Dimitri FabrègesiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersDevelopmental Biology

Katharina F. SonnenORCID

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3 papers

Recent·Most cited

Spatiotemporal proteomics reveals dynamic antagonistic gradients shaping signalling waves

Wilke H. M. Meijer, Virginia Andrade, Suzan Stelloo, Wouter M. Thomas, Marek J. van Oostrom, Balaji Srinivasan, Dimitri Fabrèges, Sita Venkataraman, Sonja D. C. Weterings, Jan-Daniël de Leede-Scheven, Eveline F. Ilcken, Kim T. J. Peters, Michiel Vermeulen, Katharina F. Sonnen

The paper uses a microfluidics and proteomics approach to study dynamic protein gradients in mouse embryos, revealing antagonistic ligand-receptor patterns that regulate Wnt oscillations and somite formation.

Nature Communications · Oct 25, 2026Peer-reviewedDevelopmental Biology

Coupling of cell proliferation to the segmentation clock ensures robust somite scaling

Marek J. van Oostrom, Yuting I. Li, Wilke H. M. Meijer, Tomas E. J. C. Noordzij, Charis Fountas, Erika Timmers, Jeroen Korving, Wouter M. Thomas, Benjamin D. Simons, Katharina F. Sonnen

The paper shows that coupling cell proliferation to the segmentation clock ensures uniform PSM growth and precise somite scaling in mouse embryos.

bioRxiv · Jan 10, 2025 · PreprintDevelopmental Biology

Unravelling differential Hes1 dynamics during axis elongation of mouse embryos through single-cell tracking

Yasmine el Azhar, Pascal Schulthess, Marek J. van Oostrom, Sonja D. C. Weterings, Wilke H. M. Meijer, Nobuko Tsuchida-Straeten, Wouter M. Thomas, Marianne Bauer, Katharina F. Sonnen

This study uses single-cell tracking to analyze Hes1 dynamics in mouse embryos, revealing distinct oscillation patterns in presomitic mesoderm and preneural tube cells.

Development · Sep 15, 2024Peer-reviewedDevelopmental Biology