Author

Xi Sun

Chinese University of Hong Kong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Abigail G. Branch· 1 shared An Ning· 1 shared Bao Ting ZhuiD· 1 shared Beibei Zhang· 1 shared Chao XueiD· 1 shared Chunxiu Chen· 1 shared Elliott B. BurdetteiD· 1 shared Eugene DouglassiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCancer Biology

Abigail G. Branch

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

GWAS Reveals Distinct Genetic Architecture of Schistosomiasis-Induced Hepatic Fibrosis with DGKG as a Key Mediator

Miao Zhou, Chao Xue, Lichao Zhang, Yunyi Hu, An Ning, Lifu Wang, Jia Shen, Langui Song, Beibei Zhang, Jiahua Liu, Yao Liao, Zebin Chen, Jehangir Khan, Zhongdao Wu, Chunxiu Chen, , Miaoxin Li

This study identifies DGKG as a key mediator of schistosomiasis-induced hepatic fibrosis through GWAS and functional validation, revealing distinct genetic architecture compared to other fibrotic diseases.

medRxiv · Mar 24, 2026 · PreprintGenetic & Genomic Medicine

Spatial Biology and Organoid Technologies Reveal a Potential Therapy-Resistant Cancer Stem Cell Population in Pancreatic Ductal Adenocarcinoma

Pritha Adhikary, Jayati L. Chakrabarti, Saptarshi Mallick, Xi Sun, Ugonna Ezuma-Igwe, Abigail G. Branch, Jiang Wang, Nicolas Braissand, Megan P. Corbett, Sangmin Kim, Rohan Kanakamedala, Willian C. Bastian, Eugene Douglass, Meenu Priya Resmi, Payton D. Stevens, , Yana L. Zavros

The paper uses spatial imaging and organoid models to identify therapy-resistant CD44v9+ cancer stem cells in PDAC and show that cabozantinib may enhance immunotherapy by altering the tumor microenvironment.

bioRxiv · May 22, 2025 · PreprintCancer Biology

Protective Effect of 2-Hydroxyestrone and2-Hydroxyestradiol Against Chemically-Induced Hepatotoxicity In Vitro and In Vivo

Xi Sun, Xiangyu Hao, Yi-Chen Jia, Qi Zhang, Yan-Yin Zhu, Yong Xiao Yang, Bao Ting Zhu

This study shows that 2-hydroxyestrone and 2-hydroxyestradiol protect against ferroptosis in hepatoma cells and acetaminophen-induced liver injury by inhibiting PDI activity and reducing NO, ROS, and lipid-ROS accumulation.

Journal of Pharmacology and Experimental Therapeutics · Nov 30, 2024Peer-reviewedPharmacology & Toxicology