Author

Yi-Chen Jia

Chinese University of Hong Kong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Bao Ting ZhuiD· 2 shared Xiangyu Hao· 2 shared Jialing Zhong· 1 shared Qi ZhangiD· 1 shared Xi Sun· 1 shared Yan-Yin Zhu· 1 shared Yong Xiao YangiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 17 mutual co-author links

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2 shared papersBiochemistry

Bao Ting ZhuORCID

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2 papers

Recent·Most cited

Characterization of the Mechanisms Underlying Sulfasalazine-Induced Ferroptotic Cell Death: Role of Protein Disulfide Isomerase-Mediated NOS Activation and NO Accumulation

Yi-Chen Jia, Jialing Zhong, Xiangyu Hao, Bao Ting Zhu

This study investigates how sulfasalazine induces ferroptosis via PDI-mediated iNOS activation and NO accumulation in rat cell lines.

Acta Biochimica et Biophysica Sinica · Jul 2, 2025Peer-reviewedBiochemistry

Protective Effect of 2-Hydroxyestrone and2-Hydroxyestradiol Against Chemically-Induced Hepatotoxicity In Vitro and In Vivo

Xi Sun, Xiangyu Hao, Yi-Chen Jia, Qi Zhang, Yan-Yin Zhu, Yong Xiao Yang, Bao Ting Zhu

This study shows that 2-hydroxyestrone and 2-hydroxyestradiol protect against ferroptosis in hepatoma cells and acetaminophen-induced liver injury by inhibiting PDI activity and reducing NO, ROS, and lipid-ROS accumulation.

Journal of Pharmacology and Experimental Therapeutics · Nov 30, 2024Peer-reviewedPharmacology & Toxicology