FOXA1 preserves cell polarity and restrains lysosome biogenesis in non-small cell lung adenocarcinoma
Xuecong Wang, B.G Zhang, Chu Sun, Meiyu Huang, Weitao Huang, Bo‐Bo Zhang, Xuan Zhang, Xia Ren, Ling Luo, Hengrui Liang, Youtao Zhou, Guifa Zhong, Shouheng Lin, Micky Daniel Tortorella, Tuan Zea Tan, , Jianxing He
This study shows FOXA1 maintains cell polarity and limits lysosome biogenesis in lung adenocarcinoma by regulating transcriptional circuits and interacting with TFE3.
bioRxiv · Apr 10, 2026 · PreprintCancer Biology