Author

Xian Yang

Hong Kong Polytechnic UniversityPrimary ORCID profile (0000-0002-1527-7673 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Xian YangiD1 paper · Georgia Institute of Technology

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:contrastive learning· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Dexin Shen· 1 shared Dongzhen Pan· 1 shared Haocheng Yang· 1 shared Huimin Xi· 1 shared Jason W.H. WongiD· 1 shared Keda ZhouiD· 1 shared Liang FangiD· 1 shared Mengyang Zhang· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCell Biology

Dexin Shen

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2 papers

Recent·Most cited

Mechanistic insights into chromatin modulation by the orphan remodeler ATRX

Suling Duan, Tsz-Fung Wong, Xian Yang, Haocheng Yang, Huimin Xi, Yanxiang Zhao, Zhong‐Ping Yao, Yuanliang Zhai, 廖健佑, Jason W.H. Wong, Tao Ni, Keda Zhou, Yang Liu

This study reveals how ATRX modulates chromatin by unwrapping nucleosomal DNA through a unique 'pin-like' structure and other features, proposing a 'climbing' mechanism for DNA translocation.

Molecular Cell · Oct 1, 2026Peer-reviewedBiochemistry

PB-scope: Contrastive learning of dynamic processing body formation reveals undefined mechanisms of approved compounds

Dexin Shen, Qionghua Zhu, Xiquan Pang, Xian Yang, Dongzhen Pan, Mengyang Zhang, Yanping Li, Zhiyuan Sun, Liang Fang, Wei Chen, Tatsuhisa Tsuboi

PB-scope uses deep learning to analyze PB dynamics and identifies drugs affecting JAK signaling pathway.

bioRxiv · Jun 14, 2025 · PreprintCell Biology