Tatsuhisa Tsuboi

This paper converts traditional binary auxotrophic markers into tunable selection tools in yeast, enabling quantitative analysis of gene expression through growth outcomes.

The paper investigates how cell size affects P-body assembly in yeast, finding a nucleation distance of 2.2 micrometers that links cell geometry to condensate formation.

PB-scope uses deep learning to analyze PB dynamics and identifies drugs affecting JAK signaling pathway.

This study shows that mitochondrial fragmentation increases protein expression noise due to stochastic co-translational targeting, and that fission-fusion processes reduce this heterogeneity.

The paper shows that gravity and mechanical forces influence mitochondrial translation by affecting signaling pathways and malonylation of the translational machinery.