Xiaohan Wang

N-Acetylglucosamine ameliorates knee osteoarthritis by enhancing UDP-GlcNAc conversion and chondrocyte DNA repair capacity

This study compares N-acetylglucosamine (GlcNAc) and glucosamine hydrochloride (GlcN·HCl) in a rat model of knee osteoarthritis, finding GlcNAc more effective in reducing inflammation, cartilage degradation, and promoting DNA repair.

CompleteBin: A transformer-based framework unlocks microbial dark matter through improved short contig binning

CompleteBin improves short contig binning in complex microbial communities, recovering more complete genomes and novel genes, with applications in environmental metagenomics.

Generative Diffusion Models for Antibody Design, Docking, and Optimization

This paper introduces a diffusion model-based pipeline for antibody design and optimization, achieving high performance in structure and sequence design and docking, validated by improved binding to flaviviruses.

Chromosome-Scale Genome Assembly Provides Insights into Speciation of Allotetraploid and Massive Biomass Accumulation of Elephant Grass (Pennisetum purpureum Schum.)

This study assembled the chromosome-scale genome of elephant grass, revealing speciation timing and genetic mechanisms underlying its rapid growth and high biomass.