Deep profiling of lupus nephritis kidneys reveals dynamic changes in myeloid cells associated with disease progression
Paul Hoover, Thomas Eisenhaure, Jeffrey B. Hodgin, William A. Apruzzese, Joseph Mears, Michael Peters, Tony Jones, Sujal I. Shah, Haniya Kamal, Rollin Leavitt, Shaun W. Jackson, Patrick J. Danaher, Deepak A. Rao, Qian Xiao, Siddarth Gurajala, , Arnon Arazi
This study uses single-cell RNA-sequencing and spatial transcriptomics to analyze myeloid cell dynamics in lupus nephritis, showing shifts in immune responses linked to disease progression.
Annals of the Rheumatic Diseases · Apr 28, 2026Peer-reviewedImmunology