OTTER: Orchestrated Transcriptomic, Tumor-xenograft (PDX/CDX), and Epigenomic Reporting Workflow
Yanhua Zheng, Xin Liu, Yingyu Yi, Xiaojun Sun, Fang Liu, Xiaojing Yan, Cheuk-Him Man, Hongcang Gu, Xiaoxue Wang, Fan Zhang
OTTER improves bisulfite deconvolution in tumor xenograft sequencing by restoring recall to 52%-54% while preserving transcriptomic accuracy.
bioRxiv · Oct 27, 2026 · PreprintBioinformatics