Author

Xiaowei Xu

Zhejiang University of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:trajectory inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Shujing LiuiD· 2 shared Yan CheniD· 2 shared Bomyi LimiD· 1 shared Chen-xin Guo· 1 shared Cheng CaoiD· 1 shared Chin Nien LeeiD· 1 shared Daniel Oh· 1 shared David E. Reynolds· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBioengineering

Shujing LiuORCID

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Author profile →

4 papers

Recent·Most cited

Live Droplet Single-Cell RNA Sequencing

David E. Reynolds, Sangmo Lee, Daniel Oh, Shailesh Senthil Kumar, Emily Huynh, Renee-Tyler T. Morales, Sydney Bracht, Phoebe Vallapureddy, Chin Nien Lee, Jianhua Lim, Renis J. Agosto Nieves, Shujing Liu, Gaochen Jin, Xiaowei Xu, Bomyi Lim, , Jina Ko

The paper introduces Live D-seq, a method for longitudinal, non-destructive single-cell RNA sequencing, and demonstrates its ability to track cellular dynamics over time.

bioRxiv · Nov 4, 2026 · PreprintBioengineering

An immunocompetent model of MCPyV-driven Merkel cell carcinoma reveals tumor evolution under immune selection

James M. Regan, Xiaomei Li, Mykaela Salvacion, Tiana T. Luo, Meng Jia, Grace Ho, Jonathan R. Xu, Shujing Liu, Zhi Huang, Xiaowei Xu, Jianxin You

This study shows that MCPyV-driven tumors evolve immune-evasive traits under immune pressure, favoring sT over LTT expression, using a mouse model of Merkel cell carcinoma.

bioRxiv · Jul 13, 2026 · PreprintCancer Biology

Protective Effect of Cannabinoid Type II Receptor Ligand on Bleomycin-Induced Pulmonary Fibrosis in Mice

Cheng Cao, Run-Lin Wang, Chen-xin Guo, Xiaowei Xu, Jia-hui Wei, Wenzhuo Cheng, Yi-zhe Yu, Jia-jie Shi, Zhi-wei Feng, Yan Chen

This study evaluates the protective effects of COCA, a CB2R ligand identified via AI-driven virtual screening, against BLM-induced pulmonary fibrosis in mice, showing reduced inflammation and fibrosis.

PLoS ONE · Feb 27, 2026Peer-reviewedPharmacology & Toxicology

EpiMII: Integrating Structure and Graph Neural Networks for MHC-II Epitope and Neoantigen Design

Jiayi Yuan, Xiaowei Xu, Ze‐Yu Sun, Tianjian Liang, Jingxuan Ge, Ruofan Jin, Xiang‐Qun Xie, Yan Chen, Tingjun Hou, Zhiwei Feng

EpiMII improves MHC-II epitope and neoantigen design by integrating structural features with graph neural networks, achieving higher accuracy and in vivo efficacy in tumor models.

bioRxiv · Apr 29, 2025 · PreprintImmunology