Author

Xingren Wang

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:CRISPR screen· 2 Approach:experimental assay· 2 Research Focus:perturbation response prediction· 2 Research Focus:cell signaling & trafficking· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Marco JostiD· 3 shared Yufang DingiD· 3 shared Alina GunaiD· 1 shared Ana Paula SchaaniD· 1 shared Ana Prado· 1 shared Angela N. PogsoniD· 1 shared Baylee J. RusselliD· 1 shared Bianca Frintu· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersGenomics

Marco JostORCID

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Author profile →

3 papers

Recent·Most cited

Blautia wexlerae Transforms Dietary Fatty Acids to Activate Enteroendocrine Signaling and Improve Metabolic Health in Mice and Humans

Yanjia Jason Zhang, Marian Tanofsky‐Kraff, Mildred-Maria Reyes, Daniel Zeve, Kigumbi J. Ehrmann, Jennifer Lee, Ana Paula Schaan, Ana Prado, Xiao Corey Ma, Megan N. Parker, Sheila M. Brady, Elisa Saint‐Denis, Karina Sharma, Bianca Frintu, Camila Richmond, , Eric J. Alm

This study identifies Blautia wexlerae's role in converting dietary fats into bioactive metabolites that enhance gut hormone secretion and improve metabolic health in mice and humans.

bioRxiv · Mar 14, 2026 · PreprintMicrobiology

Systematic identification and characterization of regulators of aryl hydrocarbon receptor signaling

Manasvi Verma, Kushaal Desai, Yufang Ding, Xingren Wang, Minwoo Bae, Seth Rakoff-Nahoum, Emily P. Balskus, Michael Andrew Fischbach, Marco Jost

This study identifies regulators of AHR signaling in hepatocytes using CRISPR screening, revealing novel mechanisms and cell-type-specific components for therapeutic targeting.

bioRxiv · Sep 15, 2025 · PreprintGenomics

Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors

Joseph M. Replogle, Jessica L. Bonnar, Angela N. Pogson, Christina R. Liem, Nolan K. Maier, Yufang Ding, Baylee J. Russell, Xingren Wang, Kun Leng, Alina Guna, Thomas M. Norman, Ryan A. Pak, Daniel M. Ramos, Michael Emmerson Ward, Luke A. Gilbert, , Marco Jost

This paper develops compact CRISPRi sgRNA libraries and optimal effectors to improve knockdown consistency and efficiency in mammalian cells.

eLife · Dec 28, 2022Peer-reviewedGenomics