Author

Xintao Wei

UConn Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 3 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:database / resource· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Organism:Drosophila· 1

Frequent Co-Authors

Sara OlsoniD· 3 shared Balaji SundararamaniD· 2 shared Brenton R. GraveleyiD· 2 shared Christopher B. BurgeiD· 2 shared Eric L. Van NostrandiD· 2 shared Gene Wei-Ming YeoiD· 2 shared Henry PrattiD· 2 shared Lijun ZhaniD· 2 shared

Activity by Year

2014-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Sara OlsonORCID

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4 papers

Recent·Most cited

A Large-Scale Binding and Functional Map of Human RNA Binding Proteins

Eric L. Van Nostrand, Peter Freese, Henry Pratt, Xiaofeng Wang, Xintao Wei, Rui Xiao, Steven M. Blue, Jiayu Chen, Neal A. L. Cody, Daniel Dominguez, Sara Olson, Balaji Sundararaman, Lijun Zhan, Cassandra A Bazile, Louis Philip Benoit Bouvrette, , Gene Wei-Ming Yeo

The paper maps and characterizes RNA elements recognized by human RNA binding proteins in K562 and HepG2 cells, expanding the catalog of functional elements in the human genome.

Nature · Jul 29, 2020Peer-reviewedGenomics

Allele-specific binding of RNA-binding proteins reveals functional genetic variants in the RNA

Ei-Wen Yang, Jae Hoon Bahn, Yun-Hua Esther Hsiao, Boon Xin Tan, Yiwei Sun, Ting Fu, Bo Zhou, Eric L. Van Nostrand, Henry Pratt, Peter Freese, Xintao Wei, Giovanni Quinones-Valdez, Alexander Eckehart Urban, Brenton R. Graveley, Christopher B. Burge, , Xinshu Grace Xiao

The paper introduces BEAPR, a computational method to detect allele-specific binding of RNA-binding proteins, showing it outperforms existing methods and identifies disease-relevant variants.

Nature Communications · Mar 22, 2019Peer-reviewedBioinformatics

Resources for the comprehensive discovery of functional RNA elements

Balaji Sundararaman, Lijun Zhan, Steven Blue, Rebecca Stanton, Keri Elkins, Sara Olson, Xintao Wei, Eric L Van Nostrand, Stephanie C Huelga, Brendan M Smalec, Xiaofeng Wang, Eurie L Hong, Jean M Davidson, Eric Lecuyer, Brenton R Graveley, Gene W Yeo

The paper develops a validated repository of 438 antibodies against 365 RBPs and confirms their specificity using shRNA constructs, providing resources for studying RBP functions.

Molecular Cell · Mar 1, 2016Peer-reviewedGenomics

Genome-wide Identification of Zero Nucleotide Recursive Splicing in Drosophila

Michael O Duff, Sara Olson, Xintao Wei, Ahmad Osman, Alex Plocik, Mohan Bolisetty, Susan Celniker, Brenton Graveley

The paper identifies 196 zero nucleotide exon ratchet points in 115 Drosophila genes using RNA-Seq data, revealing recursive splicing as a common and conserved mechanism.

bioRxiv · Jun 11, 2014Genomics