Author

Xue Han

Center for Life Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Xiaohua SheniD· 2 shared Zai Chang· 2 shared Aibin HeiD· 1 shared Fuchou TangiD· 1 shared Ge Zhan· 1 shared Hui ZhangiD· 1 shared Hui ZhengiD· 1 shared J. Yuyang Lu· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersGenomics

Xiaohua ShenORCID

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2 papers

Recent·Most cited

L1 and B1 repeats blueprint the spatial organization of chromatin

J. Yuyang Lu, Lei Chang, Tong Li, Ting Wang, Yafei Yin, Ge Zhan, Ke Zhang, Michelle Percharde, Liang Wang, Qi Peng, Pixi Yan, Hui Zhang, Xue Han, Xianju Bi, Wen Shao, , Xiaohua Shen

This study identifies L1 and B1 retrotransposons as key elements shaping the 3D chromatin structure through spatial compartmentalization in human and mouse cells.

bioRxiv · Oct 13, 2019 · PreprintGenomics

The long noncoding RNA Hand2as orchestrates heart development through regulation of precise expression of HAND2

Xue Han, Jiejie Zhang, Yaxi Liu, Xiaoying Fan, Shanshan Ai, Yingjie Luo, Xin Li, Sai Luo, Hui Zheng, Yanzhu Yue, Zai Chang, Zhongzhou Yang, Fuchou Tang, Aibin He, Xiaohua Shen

This study identifies Hand2as as a key lncRNA regulating HAND2 expression in heart development through single-cell RNA sequencing and knockout models, leading to congenital defects and perinatal lethality.

bioRxiv · Nov 26, 2018 · PreprintDevelopmental Biology