Author

Xue Wang

BGI Group (China)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Immunology· 2 Bioinformatics· 1 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 3 Organism:human· 3 Assay:scRNA-seq· 3 Approach:statistical model· 3 Research Focus:database / resource· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

Chuanyu LiuiD· 3 shared Jianhua YiniD· 3 shared Xiao Man YangiD· 3 shared Yuhui ZhengiD· 3 shared Fupeng Li· 2 shared Hanjie LiiD· 2 shared Longqi LiuiD· 2 shared Runsheng CheniD· 2 shared

Activity by Year

2026-2026 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Chuanyu LiuORCID

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5 papers

Recent·Most cited

ASOFormer: a Transformer-based model for predicting antisense oligonucleotide efficacy to support therapeutic candidate prioritization

Nicholas C. Dove, Yuhao Min, Özkan İş, Nilüfer Ertekin, Daniel P. Wickland, Xue Wang

ASOFormer predicts ASO efficacy using sequence, structure, and modification features, outperforming existing methods in accuracy and candidate prioritization.

bioRxiv · Sep 24, 2026 · PreprintBioinformatics

Single-Cell Multi-Omics Dissects Transcript Isoform and Immune Repertoire Dynamics in Human Immunosenescence

Yuhui Zheng, Ze-Hui Ren, Yafei Yang, Wenteng Liu, Fupeng Li, Yajun Zuo, Tao Zeng, Xue Wang, Xiumei Lin, Xinyue Zhu, Baibing Guan, Wenwen Zhou, Yunting Huang, Wangsheng Li, Yu Feng, , Chuanyu Liu

This study uses single-cell multi-omics to analyze transcript isoform and immune repertoire changes in aging human immune cells, identifying age-related molecular features in T cells and B cells.

Science China Life Sciences · Sep 1, 2026Peer-reviewedImmunology

Decoding Immune Reconstitution Failure in People Living with HIV through Single-cell Genomics

Yuxing Wang, Shichen Yang, Yue Yuan, Mingli Zhu, Jun Chen, Yong Bai, Shanshan Duan, Xuyang Shi, Tianyu Lu, Zongxing Yang, Zhuoli Huang, Dingyan Yan, Yuhui Zheng, Xuanchi Zhou, Jun Yan, , Chuanyu Liu

This study uses single-cell multi-omics to analyze immune reconstitution failure in HIV patients, identifying genetic and epigenetic factors and developing a predictive model.

bioRxiv · May 23, 2026 · PreprintGenetics

Transposon targeting non-coding RNA transcription targets G/C-rich tracts and is facilitated by an intrinsically disordered protein in Tetrahymena

Xia Cai, Yike Liu, Jialuo Li, Zhuoran Zhao, Xinyu Yao, Zhihao Zhai, Mingmei Liucong, Yujie Liu, Xue Wang, Kazufumi Mochizuki, Miao Tian

The paper identifies G/C-rich tracts as targets of non-coding RNA transcription in meiotic Tetrahymena micronuclei and shows that Rib1, an intrinsically disordered protein, facilitates this process through phase-separation.

Science China Life Sciences · Feb 26, 2026Peer-reviewedMolecular Biology

Single-Cell Genomics Elucidates Molecular Variations and Regulatory Mechanisms in Circulating Immune Cells

Jianhua Yin, Yuhui Zheng, Zhuoli Huang, Wenwen Zhou, Yue Yuan, Pengfei Cai, Yong Bai, Shichen Yang, Yue Gao, Shanshan Duan, Yang Wang, Zekai Xu, W H Zhang, Xinyu Zhang, Yilin Wei, , Chuanyu Liu

The paper introduces CIMA, a multi-omics atlas of human immune cells, identifying regulatory mechanisms and genetic associations across sex, age, and genetic factors.

Science · Jan 8, 2026Peer-reviewedImmunology