Atypical Chemokine Receptor DARC/ACKR1 Is Expressed Selectively by Neurons with Regional Heterogeneity and Protects against Neuroinflammation and Cognitive Impairment
V. N. Sankeerth Kanumuri, Ming Guo, Jayvon Nougaisse, Xujun Ma, Quansheng Du, Neal L. Weintraub, Yun Lei, Xin‐Yun Lu
This study identifies DARC/ACKR1 as a neuron-specific receptor that reduces neuroinflammation and cognitive impairment in mice and humans.
bioRxiv · Sep 14, 2026 · PreprintNeuroscience