Sclerostin Deficiency Alters Peripheral B Lymphocyte Responses in Mice
A. Chow, J. Mason, L. Coney, J. Bajwa, C. Carlisle, A. Zaslavsky, Y. Pellman, M. E. Garcia-Ojeda, A. Economides, G. Loots, J. O. Manilay
This study shows that sclerostin deficiency in mice leads to age-dependent changes in B cell development and immune responses, affecting both T-independent and T-dependent antigen responses.
bioRxiv · Oct 16, 2018 · PreprintImmunology