Cancer BiologybioRxivPreprint
Targeting Reductive Metabolic Shifts by T315I Mutation in BCR-ABL Myeloid Leukemia for Therapy
C. Y. Huang, Y.-H. Chung, S.-Y. Wu…·Z.-F. Chang
This study identifies metabolic shifts in T315I-Bcr-Abl CML and shows that combining JMF4073 with UK-5099 eradicates the disease in vivo.
DOI 10.1101/2022.03.22.485260