Author
Zhejiang University
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Guanqiao Zhang, Yaqi Fu, Chun Chan, Ruofan Jin, Yuxuan Yang, Lei Fu, Ruhong Zhou
NEOM improves neoantigen selection by integrating multiple strategies to enhance peptide binding affinity and immunogenic potential.
Scientific Reports · Jan 19, 2026Peer-reviewedBioinformatics
Teng Xie, Yaqi Fu, Shi-Meng Gong, Damiano Burrato, Ruhong Zhou
The paper designs high-specificity binders for pHLA complexes using a deep learning and simulation framework, achieving nanomolar potency and mutation selectivity.
bioRxiv · Oct 3, 2025 · PreprintBiophysics
Guanqiao Zhang, Yaqi Fu, Damiano Buratto, Chun Chan, Hanyao Wang, Yuanling Huang, Liquan Huang, Ruhong Zhou
AlphaVacc optimizes neoantigen peptides using deep reinforcement learning, improving binding affinity and T cell response in experimental validation.
bioRxiv · Aug 3, 2025 · PreprintBioinformatics
Zaixi Zhang, Ruofan Jin, Linlin Chao, Guangxue Xu, Yikun Zhang, Guowei Zhou, Di Yin, Yingqing Guo, Yaqi Fu, Yukang Yang, Kaixuan Huang, Xiaotong Wang, Junze Zhang, Yujie Yang, Qirong Yang, , Le Cong
RNAGenesis is a foundation model for RNA therapeutics that integrates sequence, structure, and function prediction, achieving state-of-the-art performance on multiple tasks and enabling functional RNA design.
bioRxiv · Dec 30, 2024 · PreprintBioinformatics