False discovery rate control enables trustworthy deep-learning-based de novo peptide sequencing
Zhendong Liang, Chengxin Dai, Tianze Ling, Tingpeng Yang, Yun Yang, Yeye Leng, Linhai Xie, Yonghong He, Fuchu He, Yue Wang, Cheng Chang
This paper introduces a method to control false discovery rates in deep-learning-based de novo peptide sequencing, improving reliability of peptide identifications.
bioRxiv · Jun 29, 2026 · PreprintBioinformatics