CD4 T cell surface architecture is associated with response to anti-PD-1 therapy in non-small cell lung cancer
Riccardo Cinotti, Ying Yang, Vincent van Hoef, Hanna van Ooijen, Andreas Parling, Mannon Geindreau, neda bigdeli, Mireia Crus De los Santos, Lucas Baldran-Groves, Yiming Yang, Lisa Liu, Maria Johansson, Klas Kärre, Simon Fredriksson, Luigi De Petris, Andreas Lundqvist
The paper shows that CD4 T cell surface protein organization predicts response to anti-PD-1 therapy in NSCLC, outperforming protein abundance alone.
bioRxiv · Oct 30, 2026 · PreprintImmunology