Author

Ying Feng

East China University of Science and Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

Click to filter author papers

Molecular Biology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:human· 4 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Hanhui MaiD· 4 shared Xiao XiaoiD· 3 shared Ardalan NaseriiD· 2 shared Jing ZhengiD· 2 shared Shaojie ZhangiD· 2 shared Thoru PedersoniD· 2 shared Wei XieiD· 2 shared Hongye Fu· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersMolecular Biology

Hanhui MaORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Enhancing Prime Editing Efficiency and Flexibility with Tethered and Split pegRNAs

Ying Feng, Siyuan Liu, Qiqin Mo, Xiao Xiao, Pengpeng Liu, Hanhui Ma

This study improves prime editing efficiency and flexibility by introducing tethered and split pegRNAs, achieving 2-4-fold higher mutation rates in cell lines.

Protein & Cell · Jul 15, 2022Peer-reviewedMolecular Biology

DNA binding domain undergoes dynamic and selective protein-protein interactions to facilitate CTCF insulation

Zhou Rong, Kai Tian, Huang Jie, Wenjia Duan, Hongye Fu, Ying Feng, Hui Wang, Yongpeng Jiang, Li Yuanjun, Rui Wang, Jiazhi Hu, Hanhui Ma, Zhi Qi, Xiong Ji

The paper shows that CTCF's DNA binding domain forms dynamic clusters that interact with insulator proteins and avoid transcriptional activators, revealing a mechanism for its insulation function.

bioRxiv · May 15, 2022 · PreprintMolecular Biology

Simultaneous Epigenetic Perturbation and Genome Imaging Reveal Distinct Roles of H3K9me3 in Chromatin Architecture and Transcription

Ying Feng, Yao Wang, Xiangnan Wang, Xiaohui He, Yang Chen, Ardalan Naseri, Thoru Pederson, Jing Zheng, Shaojie Zhang, Xiao Xiao, Wei Xie, Hanhui Ma

This study uses EpiGo-KRAB to introduce H3K9me3 at specific loci and shows it forms heterochromatin-like domains without widespread gene repression.

Genome biology · Dec 1, 2020Peer-reviewedMolecular Biology

CRISPR-based Live Imaging of Epigenetic Modification-Mediated Genome Reorganization

Ying Feng, Yao Wang, Yang Chen, Ardalan Naseri, Thoru Pederson, Jing Zheng, Xiao Xiao, Shaojie Zhang, Wei Xie, Hanhui Ma

The paper develops a CRISPR-based system to image epigenetic modification effects on genome organization in living cells and shows it induces genomic relocation and H3K9me3 decoration.

bioRxiv · Feb 18, 2020 · PreprintMolecular Biology