Molecular BiologybioRxivPreprint
DNA binding domain undergoes dynamic and selective protein-protein interactions to facilitate CTCF insulation
Zhou Rong, Kai Tian, Huang Jie…·Xiong Ji
The paper shows that CTCF's DNA binding domain forms dynamic clusters that interact with insulator proteins and avoid transcriptional activators, revealing a mechanism for its insulation function.
DOI 10.1101/2022.05.15.491938