Transcriptomic comparison of Drosophila snRNP biogenesis mutants: implications for Spinal Muscular Atrophy
Eric L. Garcia, Ying Wen, Kavita Praveen, A. Gregory Matera
This study compares transcriptomic changes in Drosophila snRNP biogenesis mutants to identify snRNP-dependent and Smn-specific RNA processing defects, finding differences between hypomorphic and complete loss-of-function Smn mutants.
bioRxiv · Mar 26, 2016Genomics