Author

Yu Bai

California State University, Fullerton

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Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:perturbation response prediction· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Anqi WangiD· 1 shared Chunyu Wang· 1 shared Dehua Zou· 1 shared Dongjun YangiD· 1 shared Hongmiao SuniD· 1 shared Jialin TangiD· 1 shared Jianwei Feng· 1 shared Jin Wang· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Anqi WangORCID

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2 papers

Recent·Most cited

A split-control criterion for few-shot adaptation in single-cell perturbation prediction

Wanli Liang, Yabing Yang, Qiong-Yi Zhang, Jing-Cheng Feng, Qian‐Fei Wang, Dehua Zou, Jialin Tang, Yang Liu, Siyuan Wang, Junwei Duan, Yu Bai, Yi-Fang Li, WanYang Sun, Yun-Feng Cao, Rong-Rong He

This paper introduces SafeDelta, a split-control criterion for few-shot adaptation in single-cell perturbation prediction, showing it improves reproducibility and identifies biological programs.

bioRxiv · Oct 13, 2026 · PreprintBioinformatics

Homeobox transcription factor MSX2 down-regulates ERα action to facilitate anti-estrogensensitivity in ERα+ breast cancer

Jianwei Feng, Kai Zeng, Anqi Wang, Hongmiao Sun, Zining Jin, Zining Jin, Shu Feng, Xiaodi Sun, Yu Bai, Mingcong He, Wensu Liu, Manlin Wang, Dongjun Yang, Jin Wang, Wei Liu, , Yue Zhao

The paper identifies MSX2 as a co-repressor of ERα that enhances anti-estrogen sensitivity in ER-positive breast cancer by inhibiting ER-mediated transcription.

bioRxiv · Jun 16, 2026 · PreprintMolecular Biology