Iron Status Influences Mitochondrial Disease Progression in Complex I-Deficient Mice
CJ Kelly, Reid K Couch, Vivian Ha, Camille M Bodart, Judy Wu, Sydney Huff, Nicole T Herrel, Hyunsung D. Kim, Azaad O Zimmermann, Jessica Shattuck, Yu-Chen Pan, Matt R. Kaeberlein, Anthony S. Grillo
The paper shows that iron status affects disease progression in Complex I-deficient mice, with iron restriction delaying symptoms and increasing survival.
eLife · Feb 17, 2023Peer-reviewedMolecular Biology