Author
Purdue University West Lafayette
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Mutual co-authors in cluster
8 papers
Recent·Most cited
Zichen Zhang, Wanheng Zhang, Xiaochen Yang, Yujue Li, Jinjie Lin, Chong Wu, Bingxin Zhao
Domain-grounded prompting lets GPT-5 produce genetic evidence for 13,022 drug target-indication pairs that predicts clinical success as well as expert curation, with wider coverage.
bioRxiv · Sep 1, 2026 · PreprintGenetics✦ In-depth digest
Zirui Fan, Julio A. Chirinos, Xiaochen Yang, Juan Shu, Yujue Li, Joan M. O’Brien, Walter R T Witschey, Daniel James Rader, Ruben C. Gur, Bingxin Zhao
The paper maps phenotypic and genetic links between plasma proteins and organ imaging traits using UK Biobank data, identifying associations and causal links across multiple organs.
Nature Communications · Jul 11, 2026Peer-reviewedGenetic & Genomic Medicine
Juan Shu, Rong Zheng, Julio A. Chirinos, Carlos Copana, Bingxuan Li, Zirui Fan, Xiaochen Yang, Yilin Yang, Xiyao Wang, Yujue Li, Bowei Xi C, Tengfei Li, Hongtu Zhu B, Bingxin Zhao
This study uses Mendelian randomization to identify genetic causal links between 58 diseases, 56 imaging traits, and multiple organs across 402 imaging traits and 372 clinical outcomes.
Nature Biomedical Engineering · Nov 19, 2025Peer-reviewedGenetic & Genomic Medicine
Juan Shu, Yuxin Guo, Julio A. Chirinos, Zirui Fan, Yilin Yang, Yujue Li, Xiaochen Yang, Cameron Beeche, Buxin Su, Iris Horng, Rong Zheng, Peristera Paschou, Li‐San Wang, Joan M. O’Brien, Ruben C. Gur, , Bingxin Zhao
The paper investigates organ-specific and modality-specific aging clocks using proteomic and imaging data, revealing distinct biological processes and their roles in age-related diseases.
medRxiv · May 26, 2025 · PreprintGenetic & Genomic Medicine
Jin Jin, Bingxuan Li, Xiyao Wang, Xiaochen Yang, Yujue Li, Ruofan Wang, Chenglong Ye, Juan Shu, Zirui Fan, Fei Xue, Tian Ge, Marylyn DeRiggi Ritchie, Bogdan Paşaniuc, Genevieve L. Wojcik, Bingxin Zhao
PennPRS provides a cloud platform for training polygenic risk scores without individual-level data, validated with simulations and real data across 6,000 phenotypes.
medRxiv · Feb 7, 2025 · PreprintGenetic & Genomic Medicine
Yujue Li, Fei Xue, Bingxuan Li, Yilin Yang, Zirui Fan, Juan Shu, Xiaochen Yang, Xiyao Wang, Jinjie Lin, Carlos Copana, Bingxin Zhao
The paper introduces BIGA, a cloud platform for analyzing cross-trait genetic architecture using GWAS summary statistics, enabling unified data analysis and resource sharing.
bioRxiv · Apr 28, 2023 · PreprintGenetics
Zirui Fan, Yilin Yang, Yuxin Guo, Yujue Li, Juan Shu, Xiaochen Yang, Bingxuan Li, Jinjie Lin, Qianwen Wang, Carolyn Gibson, Peristera Paschou, Tengfei Li, Philip Gehrman, Hongtu Zhu B, Bingxin Zhao
This study identifies genetic overlaps between sleep traits and multi-organ imaging biomarkers, showing strong genetic links between sleep and psychiatric disorders.
medRxiv · Sep 8, 2022 · PreprintGenetic & Genomic Medicine
Bingxin Zhao, Tengfei Li, Stephen M. Smith, Zirui Fan, Xiaochen Yang, Yilin Yang, Juan Shu, Di Xiong, Xifeng Wang, Yue Yang, Tianyou Luo, Ziliang Zhu, Yue Shan, Yujue Li, Zhenyi Wu, , Hongtu Zhu B
This study identifies genetic loci associated with functional brain networks and areas using large-scale fMRI data, linking them to cognitive traits and brain disorders.
medRxiv · Jul 27, 2021 · PreprintGenetic & Genomic Medicine