Bingxuan Li

This study identifies conformational dynamics and dimer formation in TcPINK1, showing their role in Parkin recruitment and mitophagy.

This study uses Mendelian randomization to identify genetic causal links between 58 diseases, 56 imaging traits, and multiple organs across 402 imaging traits and 372 clinical outcomes.

PennPRS provides a cloud platform for training polygenic risk scores without individual-level data, validated with simulations and real data across 6,000 phenotypes.

The paper introduces BIGA, a cloud platform for analyzing cross-trait genetic architecture using GWAS summary statistics, enabling unified data analysis and resource sharing.

The paper uses genetic data to predict imaging-derived phenotypes from the UK Biobank, creating polygenic scores that identify disease risk in external cohorts.

This study identifies genetic overlaps between sleep traits and multi-organ imaging biomarkers, showing strong genetic links between sleep and psychiatric disorders.