Author

Yuki Hashidate

Saitama University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

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Approach:contrastive learning· 1 Approach:deep learning· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1

Frequent Co-Authors

Taihei Murakami· 1 shared Yasuhiro MatsunagaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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1 shared paperBiophysics

Taihei Murakami

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1 paper

Recent·Most cited

Mechanistic Interpretability of Fine-Tuned Protein Language Models for Nanobody Thermostability Prediction

Taihei Murakami, Yuki Hashidate, Yasuhiro Matsunaga

This paper fine-tunes a protein language model on nanobody thermostability data and uses sparse autoencoders to uncover biophysical rules governing stability, identifying both known and novel stabilizing features.

Bioinformatics · Sep 18, 2026Peer-reviewedBiophysics