A Pan-pangenome illuminates complex structural variation and selection in humans, chimpanzees, and bonobos
Joana L. Rocha, Runyang Nicolas Lou, Carolina de Lima Adam, Prajna Hebbar, Scott Ferguson, Davide Bolognini, Alison N. Killilea, Kendra Hoekzema, Andrea Guarracino, Yun Deng, Nicole Soranzo, Benedict Paten, Erik P. Garrison, Alex A. Pollen, Evan E. Eichler, , Peter H. Sudmant
This study presents a pan-pangenome of humans, chimpanzees, and bonobos, revealing structural variation, selection patterns, and adaptations related to immunity and malaria resistance.
bioRxiv · Jun 8, 2026 · PreprintEvolutionary Biology