Mitochondrial control of glycerolipid synthesis by a PEP shuttle
Tadashi Yamamuro, Daisuke Katoh, Guilherme Martins Silva, Hiroshi Nishida, Satoshi Oikawa, Yusuke Higuchi, Dandan Wang, Masanori Fujimoto, Naofumi Yoshida, M. Li, Jihoon Shin, Zezhou Zhao, Jin-Seon Yook, Li Sun, Shingo Kajimura
This study identifies SLC25A35 as a mitochondrial PEP transporter that regulates glycerolipid synthesis in lipogenic cells, with implications for metabolic diseases.
Cell · Mar 17, 2026Peer-reviewedCell Biology