Specific induction of double negative B cells during protective and pathogenic immune responses
C. Ruschil, G. Gabernet, G. Lepennetier, S. Heumos, M. Kaminski, Z. Hrasko, M. Irmler, J. Beckers, U. Ziemann, S. Nahnsen, G. P. Owens, J. L. Bennett, B. Hemmer, M. C. Kowarik
The paper identifies double negative B cells as an inducible population expanded in inflammatory diseases and vaccine responses, showing clonal expansion and antigen-specific antibody production.
bioRxiv · Sep 8, 2020Immunology