IS1-related large-scale deletion of chromosomal regions harbouring oxygen-insensitive nitroreductase gene nfsB causes nitrofurantoin heteroresistance in Escherichia coli
Y. Wan, A. Sabnis, Z. Mumin, I. Potterill, E. Jauneikaite, C. S. Brown, M. J. Ellington, A. M. Edwards, S. Sriskandan
The paper identifies IS1-mediated chromosomal deletions in nfsB as a novel mechanism of nitrofurantoin heteroresistance in E. coli.
Microbial Genomics · Sep 6, 2023Peer-reviewedMicrobiology