Enterococcus faecalis OG1RF Evolution at Low pH Selects Fusidate-sensitive Mutants in Elongation Factor G and at High pH Selects Defects in Phosphate Transport
B. A. Fitzgerald, A. Wadud, Z. Slimak, J. L. Slonczewski
This study shows that E. faecalis adapts to low pH by mutating elongation factor G, reducing fusidate resistance, and adapts to high pH by mutating phosphate transport genes, reducing acid tolerance.
bioRxiv · Mar 22, 2023 · PreprintMicrobiology