Systematic Spike Sorting Errors Revealed by Juxtacellular Ground Truth in the Awake Brain
Zach Saccomano, Behnaz Khaghani, Reagan Bullins Shugg, Sam McKenzie, Daniel F English
The paper evaluates spike sorting errors in awake mice using ground-truth data and finds that false negatives increase significantly during bursting and spike overlaps, challenging conventional benchmarks.
bioRxiv · Nov 3, 2026 · PreprintNeuroscience