Single-atom inhibition of oncogenic drivers through cysteine coordination
Wencong Zhao, Zhen Chen, Kai Cao, Wendi Huo, Y. Zhang, Sixu Chen, Dongfang Xia, Qing Yuan, Peng Cao, Shaorui Sun, Xueyun Gao
This paper introduces single-atom inhibition using gold to target oncogenic proteins by coordinating with cysteine residues, showing efficacy in suppressing cancer cell growth and tumor progression.
bioRxiv · Aug 28, 2026 · PreprintMolecular Biology