Physiological learning involves intrasynaptic reorganization of GluA1-containing AMPA receptors
Marijo Jevtic, Elena Hollergschwandtner, Bryan Kartono, Yui Sugiyama, Lenka Strnadová, Ragul Ramesh, Yugo Fukazawa, Makoto Itakura, Ryuichi Shigemoto
This study shows that physiological learning in mice leads to intrasynaptic reorganization of GluA1-containing AMPA receptors at CA1 synapses, with increased density and clustering of GluA1 and reduced GluA2.
bioRxiv · Oct 23, 2026 · PreprintNeuroscience