PPP1R3B is a metabolic switch that shifts hepatic energy storage from lipid to glycogen
Kate Townsend Creasy, Minal B. Mehta, Carolin Victoria Schneider, Joseph Park, David Zhang, Swapnil V. Shewale, John S. Millar, Marijana Vujković, Nicholas J. Hand, Paul M. Titchenell, Joseph A. Baur, Daniel James Rader
This paper investigates the role of PPP1R3B in hepatic metabolism, finding it acts as a switch that promotes glycogen storage over lipid accumulation, with implications for metabolic diseases.
Science Advances · May 16, 2025Peer-reviewedMolecular Biology