Author

Lauren G. Mascibroda

The University of Texas Medical Branch at GalvestonORCID 0000-0002-1200-8849Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Eric J. WagneriD· 2 shared Alexander LeNailiD· 1 shared Alina GunaiD· 1 shared Angela N. PogsoniD· 1 shared Doron LipsoniD· 1 shared Florian C. Oberstrass· 1 shared Gila Lithwick‐YanaiiD· 1 shared Iain A. Sawyer· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersGenomics

Eric J. WagnerORCID

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2 papers

Recent·Most cited

Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq

Joseph M. Replogle, Reuben A. Saunders, Angela N. Pogson, Jeffrey A. Hussmann, Alexander LeNail, Alina Guna, Lauren G. Mascibroda, Eric J. Wagner, Karen Adelman, Gila Lithwick‐Yanai, Nika Iremadze, Florian C. Oberstrass, Doron Lipson, Jessica L. Bonnar, Marco Jost, , Jonathan S. Weissman

The paper performs genome-scale Perturb-seq to map genotype-phenotype relationships, uncovering new gene functions and stress-specific mitochondrial regulation.

Cell · Jun 9, 2022Peer-reviewedGenomics

Integrator Subunit 4 is a ‘Symplekin-like’ Scaffold that Associates with INTS9/11 to Form the Integrator Cleavage Module

Todd R. Albrecht, Sergey P. Shevtsov, Yixuan Wu, Lauren G. Mascibroda, Natoya J. Peart, Kai-Lieh Huang, Iain A. Sawyer, Liang Tong, Miroslav Dundr, Eric J. Wagner

The paper identifies INTS4 as a conserved interaction partner of INTS9/11, forming a heterotrimeric complex critical for UsnRNA biogenesis.

Nucleic Acids Research · Feb 17, 2018Peer-reviewedMolecular Biology