Bradley C. Rauscher

Dual-Mode Bio-CM2: Multimodal Computational Miniature Mesoscope for Fluorescence and Label-Free Imaging

The paper introduces dual-mode Bio-CM2, a miniature mesoscope that captures fluorescence and label-free imaging simultaneously, demonstrating its use across different organisms and biological contexts.

Bio-CM{superscript 2}: Distributed computational optics for cortex-widecellular imaging

Four miniature lenses sharing one CMOS sensor, with computational stitching, give cellular-resolution imaging over 7.5 × 10 mm^2 at video rate, resolving 3,474 mouse cortical neurons.

Visual gamma stimulation causes prolonged enhancement of low-frequency blood flow oscillations across cortical regions in mice

This study shows that visual gamma stimulation increases low-frequency blood flow oscillations in multiple cortical regions of mice, with effects lasting beyond 24 hours.

Neurovascular Impulse Response Function (IRF) during spontaneous activity differentially reflects intrinsic neuromodulation across cortical regions

The paper shows that hemodynamic responses in the cortex are influenced by neuromodulators like norepinephrine, with distinct impulse response functions for different neuromodulatory signals.

Widefield in vivo imaging system with two fluorescence and two reflectance channels, a single sCMOS detector, and shielded illumination

The paper describes a widefield in vivo imaging system for mesoscopic brain imaging, capable of capturing fluorescent and reflectance signals, and demonstrates its use in awake mice.

Visual stimulation drives retinotopic acetylcholine release in the mouse visual cortex

The paper shows visual stimulation causes retinotopic acetylcholine release in the mouse visual cortex, indicating organized cholinergic signaling.

Infrared videography of a subcutaneous knee tattoo as a simple and inexpensive method to overcome skin motion artifact in rodent kinematics

This paper introduces infrared videography of a subcutaneous tattoo as a low-cost method to reduce skin motion artifact in rodent kinematics, achieving accuracy comparable to x-ray fluoroscopy.